如何应用NMT开展新冠肺炎肝损伤治疗研究?
如何应用NMT开展新冠肺炎肝损伤治疗研究?
新冠肺炎肝损伤治疗NMT研发平台优势:
- 活体组织原位研究:NMT可实现活体组织层面研究,结果更贴近体内的真实情况。
- 能量代谢研究:提供葡萄糖、氢离子等有关能量代谢的指标,给肝损伤不同阶段的能量获取与消耗,提供直接检测依据。
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- 文献:
(1)Land SC, et al. O2 availability modulates transmembrane Ca2+ flux via second-messenger pathways in anoxia-tolerant hepatocytes. Journal of Applied Physiology.2009, 82:776-783, 1997.点击查看全文
(2)Yingbai Shen, et al. Leaf Extract from Lithocarpus polystachyus Rehd. Promote Glycogen Synthesis in T2DM .
(3)Zong-Ming Zhang, et al. Effects and mechanisms of store-operated calcium channel blockade on hepatic ischemia-reperfusion injury in rats. World J .点击查看全文
(4)ZHANG Zong-ming,et al. Abnormal mitochondrial function impairs calcium influx indiabetic mouse pancreatic beta cells. Chinese Medical Journal. 2012,125(3):502-510.点击查看全文
(5)J. Darcy MacLellan, et al. Physiological Increases in Uncoupling Protein 3 Augment Fatty Acid Oxidation and Decrease Reactive Oxygen Species Production Without Uncoupling Respiration in Muscle Cells. Diabetes. 点击查看全文
(6)D. Marshall Porterfield , et al.Oxygen consumption oscillates in single clonal pancreatic beta -cells (HIT). Diabetes.2000,49:1511-1516.点击查看全文
(7)D. Marshall Porterfield, et al. Oscillatory glucose flux in INS 1 pancreatic β cells: A selfreferencing microbiosensor study. Analytical Biochemistry. 2011,411(2): 185–193.点击查看全文
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