如何应用NMT开展新冠疫苗开发及免疫研究？

在当今的疫苗研发过程中，很多疫苗在细胞水平展现了积极的效果，但到了组织和器官水平，失败的就非常多。很重要的一个原因，就是缺少组织和器官水平的筛选模型，而非损伤微测技术恰恰弥补了这方面的不足。利用非损伤微测技术，完全可以对活体组织进行在体检测，开展免疫机理、免疫疗效的在体研究。

查看《NMT新冠疫苗及免疫机理研究应用指南》

查看《NMT如何用于新冠疫苗开发及免疫研究》视频

相关设备:

《NMT新冠疫苗及免疫机理研究系统》

《NMT新冠肺炎免疫研究工作站》

测试服务:

《疫苗及免疫机理NMT体验与测试服务》

《免疫研究NMT体验与测试服务》

培训讲座：

《疫苗及免疫机理培训班》

《免疫研究培训班》

文献

（1）D. Marshall Porterfield , et al.Oxygen consumption oscillates in single clonal pancreatic beta -cells (HIT). Diabetes.2000,49:1511-1516.点击查看全文

（2）ZHANG Zong-ming,et al. Abnormal mitochondrial function impairs calcium influx in
diabetic mouse pancreatic beta cells. Chin Med J .2012,125(3):502-510.点击查看全文

（3）J. Darcy MacLellan, et al. Physiological Increases in Uncoupling Protein 3 Augment Fatty Acid Oxidation and Decrease Reactive Oxygen Species Production Without Uncoupling Respiration in Muscle Cells. Diabetes. 2005,54:2343-2350.点击查看全文

（4）D. Marshall Porterfield, et al. Oscillatory glucose flux in INS 1 pancreatic β cells: A selfreferencing microbiosensor study. Analytical Biochemistry. 2011,411(2): 185–193.点击查看全文

（5）Yingbai Shen, et al. Leaf Extract from Lithocarpus polystachyus Rehd. Promote Glycogen Synthesis in T2DM Mice. PLoS One. DOI:10.1371/journal.pone.0166557 2016.点击查看全文

（6）Georgina Valencia-Cruz et al.Kbg and Kv1.3 channels mediate potassium efflux in the early phase of apoptosis in Jurkat T lymphocytes.American Journal of Physiology - Cell Physiology, 2009,297(6):C1544-C1553.点击查看全文

（7）ZHANG Zong-ming,et al. Abnormal mitochondrial function impairs calcium influx in.点击查看全文

（8）J. Darcy MacLellan, et al. Physiological Increases in Uncoupling Protein 3 Augment Fatty Acid Oxidation and Decrease Reactive Oxygen Species Production Without Uncoupling Respiration in Muscle Cells. Diabetes. 2005,54:2343-2350.点击查看全文

（9）D. Marshall Porterfield , et al.Oxygen consumption oscillates in single clonal pancreatic beta -cells (HIT). Diabetes.2000,49:1511-1516.点击查看全文

(10)D. Marshall Porterfield, et al. Oscillatory glucose flux in INS 1 pancreatic β cells: A selfreferencing microbiosensor study. Analytical Biochemistry. 2011,411(2): 185–193.点击查看全文

(11)Yingbai Shen, et al. Leaf Extract from Lithocarpus polystachyus Rehd. Promote Glycogen Synthesis in T2DM Mice. PLoS One. DOI:10.1371/journal.pone.0166557 2016.点击查看全文

(12)Georgina Valencia-Cruz et al.Kbg and Kv1.3 channels mediate potassium efflux in the early phase of apoptosis in Jurkat T lymphocytes.American Journal of Physiology - Cell Physiology, 2009,297(6):C1544-C1553.点击查看全文